Microsoft .NET Desktop Runtime enables you to run existing Windows desktop applications. This release includes the .NET Runtime, you do not need to install it separately.

Microsoft .NET Desktop Runtime redistributable package installs the .NET Desktop Runtime and associated files required to run many applications that use this programming language.
This is Microsoft's comprehensive and consistent programming model for building applications that have visually stunning user experiences, seamless and secure communication, and the ability to model various business processes.
The .NET Desktop Runtime also includes the .NET Runtime.